Differences in DNA methylation profile of Th1 and Th2 cytokine genes are associated with tolerance acquisition in children with IgE-mediated cow’s milk allergy

Differences in DNA methylation profile of Th1 and Th2 cytokine genes are associated with tolerance acquisition in children with IgE-mediated cow’s milk allergy

Epigenetic changes in DNA methylation could regulate the expression of several allergy-related genes. We investigated whether tolerance acquisition in children with immunoglobulin E (IgE)-mediated cow's milk allergy (CMA) is characterized by a specific DNA methylation profile of Th2 (IL-4, IL-5...

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Autors principals: Roberto Berni Canani, Lorella Paparo, Rita Nocerino, Linda Cosenza, Vincenza Pezzella, Margherita Di Costanzo, Mario Capasso, Valentina Del Monaco, Valeria D’Argenio, Luigi Greco, Francesco Salvatore
Format: Artigo
Idioma:anglès
Publicat: 2015
Accés en línia:https://doi.org/10.1186/s13148-015-0070-8
https://clinicalepigeneticsjournal.biomedcentral.com/counter/pdf/10.1186/s13148-015-0070-8
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https://doi.org/10.1186/s13148-015-0070-8
https://clinicalepigeneticsjournal.biomedcentral.com/counter/pdf/10.1186/s13148-015-0070-8

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