7 beta-hydroperoxycholest-5-en-3 beta-ol, a component of human atherosclerotic lesions, is the primary cytotoxin of oxidized human low density lipoprotein.

Modification of low density lipoprotein (LDL) by free radical oxidation renders this molecular complex cytotoxic. Oxidized lipoproteins exist in vivo in atherosclerotic lesions and in the plasma of diabetic animals, suggesting that lipoprotein-induced tissue damage may occur in certain diseases. We...

全面介紹

Saved in:
書目詳細資料
Main Authors: G M Chisolm, Guoping Ma, K. C. Irwin, LJ Martin, Karl Gunderson, L. F. Linberg, Diane W. Morel, Paul E. DiCorleto
格式: Artigo
語言:英语
出版: 1994
在線閱讀:https://doi.org/10.1073/pnas.91.24.11452
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!