7 beta-hydroperoxycholest-5-en-3 beta-ol, a component of human atherosclerotic lesions, is the primary cytotoxin of oxidized human low density lipoprotein.

Modification of low density lipoprotein (LDL) by free radical oxidation renders this molecular complex cytotoxic. Oxidized lipoproteins exist in vivo in atherosclerotic lesions and in the plasma of diabetic animals, suggesting that lipoprotein-induced tissue damage may occur in certain diseases. We...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: G M Chisolm, Guoping Ma, K. C. Irwin, LJ Martin, Karl Gunderson, L. F. Linberg, Diane W. Morel, Paul E. DiCorleto
Fformat: Artigo
Iaith:Saesneg
Cyhoeddwyd: 1994
Mynediad Ar-lein:https://doi.org/10.1073/pnas.91.24.11452
Tagiau: Ychwanegu Tag
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