BDNF gene therapy induces auditory nerve survival and fiber sprouting in deaf Pou4f3 mutant mice
Current therapy for patients with hereditary absence of cochlear hair cells, who have severe or profound deafness, is restricted to cochlear implantation, a procedure that requires survival of the auditory nerve. Mouse mutations that serve as models for genetic deafness can be utilized for developin...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | H. Fukui, Hiu-Tung Wong, Lisa A. Beyer, Ben Case, Donald L. Swiderski, Adriana Di Polo, Allen F. Ryan, Yehoash Raphael |
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Μορφή: | Artigo |
Γλώσσα: | Αγγλικά |
Έκδοση: |
2012
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Διαθέσιμο Online: | https://doi.org/10.1038/srep00838 https://www.nature.com/articles/srep00838.pdf |
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BDNF gene therapy induces auditory nerve survival and fiber sprouting in deaf Pou4f3 mutant mice
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