Trabectedin and Plitidepsin: Drugs from the Sea that Strike the Tumor Microenvironment
The prevailing paradigm states that cancer cells acquire multiple genetic mutations in oncogenes or tumor suppressor genes whose respective activation/up-regulation or loss of function serve to impart aberrant properties, such as hyperproliferation or inhibition of cell death. However, a tumor is no...
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Autori principali: | , , |
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Natura: | Revisão |
Lingua: | inglese |
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2014
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Accesso online: | https://doi.org/10.3390/md12020719 https://www.mdpi.com/1660-3397/12/2/719/pdf?version=1424782634 |
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