Pregnenolone Sulfate Restores the Glutamate-Nitric-Oxide-cGMP Pathway and Extracellular GABA in Cerebellum and Learning and Motor Coordination in Hyperammonemic Rats

Around 40% of cirrhotic patients show minimal hepatic encephalopathy (MHE), with mild cognitive impairment which reduces their quality of life and life span. Treatment of MHE is unsatisfactory, and there are no specific treatments for the neurological alterations in MHE. Hyperammonemia is the main c...

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Main Authors: Alba González‐Usano, Omar Cauli, Ana Agustí, Vicente Felipo
Format: Artigo
Jezik:angleščina
Izdano: 2013
Online dostop:https://doi.org/10.1021/cn400168y
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