Pregnenolone Sulfate Restores the Glutamate-Nitric-Oxide-cGMP Pathway and Extracellular GABA in Cerebellum and Learning and Motor Coordination in Hyperammonemic Rats
Around 40% of cirrhotic patients show minimal hepatic encephalopathy (MHE), with mild cognitive impairment which reduces their quality of life and life span. Treatment of MHE is unsatisfactory, and there are no specific treatments for the neurological alterations in MHE. Hyperammonemia is the main c...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | anglais |
| Publié: |
2013
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| Accès en ligne: | https://doi.org/10.1021/cn400168y |
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