Mitochondrial Electron Transport Is the Cellular Target of the Oncology Drug Elesclomol
Elesclomol is a first-in-class investigational drug currently undergoing clinical evaluation as a novel cancer therapeutic. The potent antitumor activity of the compound results from the elevation of reactive oxygen species (ROS) and oxidative stress to levels incompatible with cellular survival. Ho...
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| Main Authors: | , , , , , , , , , , , , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2012
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| 在线阅读: | https://doi.org/10.1371/journal.pone.0029798 https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0029798&type=printable |
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