ERK-mediated phosphorylation of Thr735 in TNFα-converting enzyme and its potential role in TACE protein trafficking

Tumor necrosis factor alpha-converting enzyme (TACE/ADAM17) has been implicated in the inducible shedding of numerous cell surface proteins. In light of this, the regulation of TACE catalytic activation and protein maturation has recently received considerable interest in the context of extracellula...

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Auteurs principaux: Surinder M. Soond, Bethany Everson, David W. H. Riches, Gillian Murphy
Format: Artigo
Langue:anglais
Publié: 2005
Accès en ligne:https://doi.org/10.1242/jcs.02357
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