ERK-mediated phosphorylation of Thr735 in TNFα-converting enzyme and its potential role in TACE protein trafficking

Tumor necrosis factor alpha-converting enzyme (TACE/ADAM17) has been implicated in the inducible shedding of numerous cell surface proteins. In light of this, the regulation of TACE catalytic activation and protein maturation has recently received considerable interest in the context of extracellula...

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Bibliographic Details
Main Authors: Surinder M. Soond, Bethany Everson, David W. H. Riches, Gillian Murphy
Format: Artigo
Language:English
Published: 2005
Online Access:https://doi.org/10.1242/jcs.02357
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