Molecular Model of Human CYP21 Based on Mammalian CYP2C5: Structural Features Correlate with Clinical Severity of Mutations Causing Congenital Adrenal Hyperplasia

Enhanced understanding of structure-function relationships of human 21-hydroxylase, CYP21, is required to better understand the molecular causes of congenital adrenal hyperplasia. To this end, a structural model of human CYP21 was calculated based on the crystal structure of rabbit CYP2C5. All but t...

全面介紹

Saved in:
書目詳細資料
Main Authors: Tiina Robins, Jonas Carlsson, Maria Sunnerhagen, Anna Wedell, Bengt Persson
格式: Artigo
語言:英语
出版: 2006
在線閱讀:https://doi.org/10.1210/me.2006-0172
https://academic.oup.com/mend/article-pdf/20/11/2946/10720481/mend2946.pdf
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!