Control of T Cell-mediated Autoimmunity by Metabolite Flux to N-Glycan Biosynthesis

Autoimmunity is a complex trait disease where the environment influences susceptibility to disease by unclear mechanisms. T cell receptor clustering and signaling at the immune synapse, T cell proliferation, CTLA-4 endocytosis, T(H)1 differentiation, and autoimmunity are negatively regulated by beta...

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Príomhchruthaitheoirí: Ani Grigorian, Sung‐Uk Lee, Wenqiang Tian, I.-Ju Chen, Guoyan Gao, Richard Mendelsohn, James W. Dennis, Michael A. Demetriou
Formáid: Artigo
Teanga:Béarla
Foilsithe / Cruthaithe: 2007
Rochtain ar líne:https://doi.org/10.1074/jbc.m701890200
http://www.jbc.org/article/S0021925817473820/pdf
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