Optimal Temperature Selection for Mutation Detection by Denaturing HPLC and Comparison to Single-Stranded Conformation Polymorphism and Heteroduplex Analysis

Denaturing HPLC (DHPLC) is a semi-automated method for detecting unknown DNA sequence variants. The sensitivity of the method is dependent on the temperature at which the analysis is undertaken, the selection of which is dependent on operator experience. To circumvent this, software has been develop...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Alistair C. Jones, Jehannine Austin, Nancy F. Hansen, Bastiaan Hoogendoorn, Peter J. Oefner, Jeremy P. Cheadle, Michael O’Donovan
Fformat: Artigo
Iaith:Saesneg
Cyhoeddwyd: 1999
Mynediad Ar-lein:https://doi.org/10.1093/clinchem/45.8.1133
https://academic.oup.com/clinchem/article-pdf/45/8/1133/31929085/clinchem1133.pdf
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!