Differential effects of Kv7 (M‐) channels on synaptic integration in distinct subcellular compartments of rat hippocampal pyramidal neurons

The K(V)7/M-current is an important determinant of neuronal excitability and plays a critical role in modulating action potential firing. In this study, using a combination of electrophysiology and computational modelling, we show that these channels selectively influence peri-somatic but not dendri...

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Hlavní autoři: Mala M. Shah, Michele Migliore, David A. Brown
Médium: Artigo
Jazyk:angličtina
Vydáno: 2011
On-line přístup:https://doi.org/10.1113/jphysiol.2011.220913
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