G‐protein‐coupled receptor heteromers: function and ligand pharmacology

Almost all existing models for G‐protein‐coupled receptors (GPCRs) are based on the occurrence of monomers. Recent studies show that many GPCRs are dimers. Therefore for some receptors dimers and not monomers are the main species interacting with hormones/neurotransmitters/drugs. There are reasons f...

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Bibliografiska uppgifter
Huvudupphovsmän: Rafael Franco, Vicent Casadó, Antoni Cortés, Josefa Mallol, Francisco Ciruela, Sergi Ferré, Carme Lluı́s, Enric I. Canela
Materialtyp: Revisão
Språk:engelska
Publicerad: 2007
Länkar:https://doi.org/10.1038/sj.bjp.0707571
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1038/sj.bjp.0707571
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