Processing and presentation of self and foreign antigens by the renal proximal tubule.

The renal proximal tubule (PT) in many ways resembles an APC. The PT is one of the few epithelial cells in the body reported to constitutively express the class II MHC molecules required to present Ag to CD4+ T cells. We questioned whether the PT could function as an APC in vitro and in vivo. Fluore...

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Bibliographic Details
Main Authors: David Hagerty, Paul M. Allen
Format: Artigo
Language:English
Published: 1992
Online Access:https://doi.org/10.4049/jimmunol.148.8.2324
https://journals.aai.org/jimmunol/article-pdf/148/8/2324/1056283/2324.pdf
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