The TLR9 Ligand CpG Promotes the Acquisition of <i>Plasmodium falciparum</i>-Specific Memory B Cells in Malaria-Naive Individuals

The TLR9 Ligand CpG Promotes the Acquisition of <i>Plasmodium falciparum</i>-Specific Memory B Cells in Malaria-Naive Individuals

Abstract Despite the central role of memory B cells (MBC) in protective immune responses, little is understood about how they are acquired in naive individuals in response to Ag exposure, and how this process is influenced by concurrent activation of the innate immune system’s TLR. In this longitudi...

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Autors principals: Peter D. Crompton, Marko Mircetic, Greta E. Weiss, Amy Baughman, Chiung‐Yu Huang, David J. Topham, John J. Treanor, Igñacio Sanz, F. Eun-Hyung Lee, Anna P. Durbin, Kazutoyo Miura, David L. Narum, Ruth D. Ellis, Elissa Malkin, Gregory Mullen, Louis H. Miller, Laura B. Martin, Susan K. Pierce
Format: Artigo
Idioma:anglès
Publicat: 2009
Accés en línia:https://doi.org/10.4049/jimmunol.0803596
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https://doi.org/10.4049/jimmunol.0803596

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