Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies

Background: In addition to HLA genetic incompatibility, non-HLA difference between donor and recipients of transplantation leading to allograft rejection are now becoming evident. We aimed to create a unique genome-wide platform to facilitate genomic research studies in transplant-related studies. W...

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Hlavní autoři: Leslie A. Lange, Jessica van Setten, Shefali S. Verma, Yontao Lu, Michael V. Holmes, Hui Gao, Monkol Lek, Nikhil Nair, Hareesh Chandrupatla, Bao‐Li Chang, Konrad J. Karczewski, Chanel Wong, Maedeh Mohebnasab, Eyas H. Mukhtar, Randy Phillips, Vinicius Tragante, Cuiping Hou, Laura Steel, Takesha Lee, James Garifallou, Toumy Guettouche, Hongzhi Cao, Weihua Guan, Aubree Himes, Jacob van Houten, Andrew Pasquier, Reina Yu, Elena Carrigan, Michael B. Miller, David P. Schladt, Abdullah Akdere, Ana González, Kelsey M. Llyod, Daniel E. McGinn, Abhinav Gangasani, Zach Michaud, Abigail Colasacco, James Snyder, Kelly Thomas, Tiancheng Wang, Baolin Wu, Alhusain J. Alzahrani, Amein K. Al‐Ali, Fahad Al‐Muhanna, Abdullah M. Al‐Rubaish, Samir Al-Mueilo, Dimitri Monos, Barbara Murphy, Kim M. Olthoff, Cisca Wijmenga, Teresa Webster, Malek Kamoun, Suganthi Balasubramanian, Matthew B. Lanktree, William S. Oetting, Pablo García‐Pavía, Daniel G. MacArthur, Paul I. W. de Bakker, Hákon Hákonarson, Kelly A. Birdwell, Pamala A. Jacobson, Marylyn D. Ritchie, Folkert W. Asselbergs, Ajay K. Israni, Abraham Shaked, Brendan J. Keating
Médium: Artigo
Jazyk:angličtina
Vydáno: 2015
On-line přístup:https://doi.org/10.1186/s13073-015-0211-x
https://genomemedicine.biomedcentral.com/counter/pdf/10.1186/s13073-015-0211-x
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