Safety and Efficacy of Tocilizumab for the Treatment of Rheumatoid Arthritis

Because of the pathological role of IL-6 in rheumatoid arthritis (RA), tocilizumab (TCZ), a humanized anti-IL-6 receptor monoclonal antibody, was expected to improve inflammation and joint destruction of RA. Indeed, randomized clinical trials demonstrated the clinical efficacy of TCZ as monotherapy...

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Bibliographic Details
Main Authors: Atsushi Ogata, Tôru Hirano, Yoshihiro Hishitani, Toshio Tanaka
Format: Artigo
Language:English
Published: 2012
Online Access:https://doi.org/10.4137/cmamd.s7371
https://journals.sagepub.com/doi/pdf/10.4137/CMAMD.S7371
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