Fiberless Recombinant Adenoviruses: Virus Maturation and Infectivity in the Absence of Fiber

ABSTRACT In vivo targeting of therapeutic genes to specific tissues has become a major issue in gene therapy, in particular when recombinant adenovirus vectors are used. Restriction of the viral tropism to selected cell types requires the abrogation of the interaction between the viral fiber and its...

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Main Authors: Valérie Legrand, Danièle Spehner, Y. Schlesinger, Nathalie Settelen, Andréa Pavirani, Majid Mehtali
格式: Artigo
語言:英语
出版: 1999
在線閱讀:https://doi.org/10.1128/jvi.73.2.907-919.1999
https://jvi.asm.org/content/jvi/73/2/907.full.pdf
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