Fiberless Recombinant Adenoviruses: Virus Maturation and Infectivity in the Absence of Fiber
ABSTRACT In vivo targeting of therapeutic genes to specific tissues has become a major issue in gene therapy, in particular when recombinant adenovirus vectors are used. Restriction of the viral tropism to selected cell types requires the abrogation of the interaction between the viral fiber and its...
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Main Authors: | , , , , , |
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格式: | Artigo |
語言: | 英语 |
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1999
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在線閱讀: | https://doi.org/10.1128/jvi.73.2.907-919.1999 https://jvi.asm.org/content/jvi/73/2/907.full.pdf |
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