Central Role for MyD88 in the Responses of Microglia to Pathogen-Associated Molecular Patterns
Abstract Microglia, the innate immune effector cells of the CNS parenchyma, express TLR that recognize conserved motifs of microorganisms referred to as pathogen-associated molecular patterns (PAMP). All TLRs identified to date, with the exception of TLR3, use a common adaptor protein, MyD88, to tra...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2006
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| Online Access: | https://doi.org/10.4049/jimmunol.176.11.6802 |
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