Conditional U1 Gene Silencing in Toxoplasma gondii

The functional characterisation of essential genes in apicomplexan parasites, such as Toxoplasma gondii or Plasmodium falciparum, relies on conditional mutagenesis systems. Here we present a novel strategy based on U1 snRNP-mediated gene silencing. U1 snRNP is critical in pre-mRNA splicing by defini...

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Váldodahkkit: Manuela S. Pieperhoff, Gurman S. Pall, Elena Jimenéz‐Ruiz, Sujaan Das, Carmen Melatti, Matthew Gow, Eleanor Wong, Joanne Heng, Sylke Müller, Michael J. Blackman, Markus Meissner
Materiálatiipa: Artigo
Giella:eaŋgalasgiella
Almmustuhtton: 2015
Liŋkkat:https://doi.org/10.1371/journal.pone.0130356
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0130356&type=printable
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