The cytoplasmic domain of CD4 is sufficient for its down-regulation from the cell surface by human immunodeficiency virus type 1 Nef

Human immunodeficiency virus type 1 Nef down-regulates surface expression of murine and human CD4 but not human CD8. We recently reported that the cytoplasmic domain of CD4 is required for its down-regulation by Nef. Using a chimeric molecule composed of the extracellular and transmembrane domains o...

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Main Authors: Stephen J. Anderson, Marc E. Lenburg, Nathaniel R. Landau, J. Victor Garcia
格式: Artigo
语言:英语
出版: 1994
在线阅读:https://doi.org/10.1128/jvi.68.5.3092-3101.1994
https://jvi.asm.org/content/jvi/68/5/3092.full.pdf
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