Arsenite and cadmium(II) as probes of glucocorticoid receptor structure and function.
Low concentrations of arsenite, but not arsenate, and Cd2+ blocked steroid binding to the glucocorticoid receptors of HTC cells. Inhibition by arsenite was faster and occurred at lower concentrations than for Cd2+. Half-maximal inhibition of [3H]dexamethasone binding was seen after a 30-min preincub...
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| Main Authors: | , , |
|---|---|
| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
1990
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| 在线阅读: | https://doi.org/10.1016/s0021-9258(19)39922-3 |
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