Cloning and sequencing of complementary DNAs encoding the alpha-subunit of translational initiation factor eIF-2. Characterization of the protein and its messenger RNA.

A clone encoding the a-subunit of eukaryotic initiation factor 2 (eIF-2a) was isolated from a Xgtl l expression library of rat brain cDNAs.The fusion protein expressed by the recombinant phage reacts with eIF-2a antiserum except when the serum is preadsorbed with pure eIF-2.The translation of hybrid...

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Bibliographic Details
Main Authors: H Ernst, Roger F. Duncan, J W Hershey
Format: Artigo
Language:English
Published: 1987
Online Access:https://doi.org/10.1016/s0021-9258(19)75772-x
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