The C-terminal Domain (CTD) of Human DNA Glycosylase NEIL1 Is Required for Forming BERosome Repair Complex with DNA Replication Proteins at the Replicating Genome
The human DNA glycosylase NEIL1 was recently demonstrated to initiate prereplicative base excision repair (BER) of oxidized bases in the replicating genome, thus preventing mutagenic replication. A significant fraction of NEIL1 in cells is present in large cellular complexes containing DNA replicati...
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Main Authors: | , , , , , , , , , , |
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格式: | Artigo |
语言: | 英语 |
出版: |
2015
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在线阅读: | https://doi.org/10.1074/jbc.m115.642918 http://www.jbc.org/article/S0021925820421155/pdf |
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