The C-terminal Domain (CTD) of Human DNA Glycosylase NEIL1 Is Required for Forming BERosome Repair Complex with DNA Replication Proteins at the Replicating Genome

The human DNA glycosylase NEIL1 was recently demonstrated to initiate prereplicative base excision repair (BER) of oxidized bases in the replicating genome, thus preventing mutagenic replication. A significant fraction of NEIL1 in cells is present in large cellular complexes containing DNA replicati...

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Hlavní autoři: Pavana M. Hegde, Arijit Dutta, Shiladitya Sengupta, Joy Mitra, Sanjay Adhikari, Alan E. Tomkinson, Guo‐Min Li, István Boldogh, Tapas K. Hazra, Sankar Mitra, Muralidhar L. Hegde
Médium: Artigo
Jazyk:angličtina
Vydáno: 2015
On-line přístup:https://doi.org/10.1074/jbc.m115.642918
http://www.jbc.org/article/S0021925820421155/pdf
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