Repertoire Requirements of CD4+ T Cells That Prevent Spontaneous Autoimmune Encephalomyelitis

Abstract Spontaneous experimental autoimmune encephalomyelitis arises in 100% of mice exclusively harboring myelin basic protein-specific T cells, and can be prevented by a single injection of CD4+ T cells obtained from normal donors. Given the powerful regulatory effect of the transferred T cells,...

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Autori principali: Danyvid Olivares‐Villagómez, Allen Wensky, Yijie Wang, Juan J. Lafaille
Natura: Artigo
Lingua:inglese
Pubblicazione: 2000
Accesso online:https://doi.org/10.4049/jimmunol.164.10.5499
https://journals.aai.org/jimmunol/article-pdf/164/10/5499/1113219/5499.pdf
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