Repertoire Requirements of CD4+ T Cells That Prevent Spontaneous Autoimmune Encephalomyelitis
Abstract Spontaneous experimental autoimmune encephalomyelitis arises in 100% of mice exclusively harboring myelin basic protein-specific T cells, and can be prevented by a single injection of CD4+ T cells obtained from normal donors. Given the powerful regulatory effect of the transferred T cells,...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2000
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| Online Access: | https://doi.org/10.4049/jimmunol.164.10.5499 https://journals.aai.org/jimmunol/article-pdf/164/10/5499/1113219/5499.pdf |
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