Lentivirus-mediated gene transfer induces long-term transgene expression of BMP-2 in vitro and new bone formation in vivo

We examined the potential of ex vivo gene therapy to enhance bone repair using lentiviral vectors encoding either enhanced green fluorescent protein (EGFP) as a reporter gene or bone morphogenetic protein-2 (BMP-2) downstream of either the cytomegalovirus immediate early (CMV) promoter or the murine...

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書誌詳細
主要な著者: Osamu Sugiyama, Dong Sung An, Sam Kung, Brian T. Feeley, Seth C. Gamradt, Nancy Q. Liu, Irvin S. Y. Chen, Jay R. Lieberman
フォーマット: Artigo
言語:英語
出版事項: 2004
オンライン・アクセス:https://doi.org/10.1016/j.ymthe.2004.10.019
https://www.cell.com/article/S1525001604015114/pdf
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