Lentivirus-mediated gene transfer induces long-term transgene expression of BMP-2 in vitro and new bone formation in vivo

We examined the potential of ex vivo gene therapy to enhance bone repair using lentiviral vectors encoding either enhanced green fluorescent protein (EGFP) as a reporter gene or bone morphogenetic protein-2 (BMP-2) downstream of either the cytomegalovirus immediate early (CMV) promoter or the murine...

Cur síos iomlán

Sábháilte in:
Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Osamu Sugiyama, Dong Sung An, Sam Kung, Brian T. Feeley, Seth C. Gamradt, Nancy Q. Liu, Irvin S. Y. Chen, Jay R. Lieberman
Formáid: Artigo
Teanga:Béarla
Foilsithe / Cruthaithe: 2004
Rochtain ar líne:https://doi.org/10.1016/j.ymthe.2004.10.019
https://www.cell.com/article/S1525001604015114/pdf
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