Angiotensin-converting Enzyme Degrades Alzheimer Amyloid β-Peptide (Aβ); Retards Aβ Aggregation, Deposition, Fibril Formation; and Inhibits Cytotoxicity

Angiotensin-converting Enzyme Degrades Alzheimer Amyloid β-Peptide (Aβ); Retards Aβ Aggregation, Deposition, Fibril Formation; and Inhibits Cytotoxicity

We have demonstrated that the angiotensin-converting enzyme (ACE) genotype is associated with Alzheimer's disease (AD) in the Japanese population (1Hu J. Miyatake F. Aizu Y. Nakagawa H. Nakamura S. Tamaoka A. Takahashi R. Urakami K. Shoji M. Neurosci. Lett. 1999; 277: 65-67Crossref PubMed Scopu...

תיאור מלא

שמור ב:

מידע ביבליוגרפי
Main Authors:	Jianguo Hu, Akira Igarashi, Makiko Kamata, Hachiro Nakagawa
פורמט:	Artigo
שפה:	אנגלית
יצא לאור:	2001
גישה מקוונת:	https://doi.org/10.1074/jbc.m104068200 http://www.jbc.org/article/S0021925819402937/pdf
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים

The N‐terminal active centre of human angiotensin‐converting enzyme degrades Alzheimer amyloid β‐peptide
מאת: Ryutaro Oba, et al.
יצא לאור: (2005)

Angiotensin-Converting Enzyme Converts Amyloid β-Protein 1–42 (Aβ(1–42)) to Aβ(1–40), and Its Inhibition Enhances Brain Aβ Deposition
מאת: Zou, Kun, et al.
יצא לאור: (2007)

Charge Dependent Retardation of Amyloid β Aggregation by Hydrophilic Proteins
מאת: Assarsson, Anna, et al.
יצא לאור: (2014)

Charge Dependent Retardation of Amyloid β Aggregation by Hydrophilic Proteins
מאת: Anna Assarsson, et al.
יצא לאור: (2014)

New Insights on How Metals Disrupt Amyloid β-Aggregation and Their Effects on Amyloid-β Cytotoxicity
מאת: Yuji Yoshiike, et al.
יצא לאור: (2001)

Angiotensin-Converting Enzyme Converts Amyloid β-Protein 1–42 (Aβ<sub>1–42</sub>) to Aβ<sub>1–40</sub>, and Its Inhibition Enhances Brain Aβ Deposition
מאת: Kun Zou, et al.
יצא לאור: (2007)

Preventing β-amyloid fibrillization and deposition: β-sheet breakers and pathological chaperone inhibitors
מאת: Wisniewski, Thomas, et al.
יצא לאור: (2008)

Zinc as chaperone-mimicking agent for retardation of amyloid β peptide fibril formation
מאת: Abelein, Axel, et al.
יצא לאור: (2015)

Zinc as chaperone-mimicking agent for retardation of amyloid β peptide fibril formation
מאת: Axel Abelein, et al.
יצא לאור: (2015)

Microglia convert aggregated amyloid-β into neurotoxic forms through the shedding of microvesicles
מאת: Joshi, P, et al.
יצא לאור: (2014)

Microglia convert aggregated amyloid-β into neurotoxic forms through the shedding of microvesicles
מאת: P. Joshi, et al.
יצא לאור: (2013)

Aβ42-to-Aβ40- and Angiotensin-converting Activities in Different Domains of Angiotensin-converting Enzyme
מאת: Zou, Kun, et al.
יצא לאור: (2009)

Aβ42-to-Aβ40- and Angiotensin-converting Activities in Different Domains of Angiotensin-converting Enzyme
מאת: Kun Zou, et al.
יצא לאור: (2009)

TMPyP Inhibits Amyloid-β Aggregation and Alleviates Amyloid-Induced Cytotoxicity
מאת: Fan, Yujuan, et al.
יצא לאור: (2017)

Regulation of Steady-state β-Amyloid Levels in the Brain by Neprilysin and Endothelin-converting Enzyme but Not Angiotensin-converting Enzyme
מאת: Elizabeth A. Eckman, et al.
יצא לאור: (2006)

The Serpin-Enzyme Complex Receptor Recognizes Soluble, Nontoxic Amyloid-β Peptide but Not Aggregated, Cytotoxic Amyloid-β Peptide
מאת: Kimberly Boland, et al.
יצא לאור: (1996)

TDP-43 expression influences amyloid β plaque deposition and tau aggregation
מאת: Davis, Stephani A., et al.
יצא לאור: (2017)

TDP-43 expression influences amyloidβ plaque deposition and tau aggregation
מאת: Stephani A. Davis, et al.
יצא לאור: (2017)

Reduced Lipid Bilayer Thickness Regulates the Aggregation and Cytotoxicity of Amyloid-β
מאת: Korshavn, Kyle J., et al.
יצא לאור: (2017)

Reduced Lipid Bilayer Thickness Regulates the Aggregation and Cytotoxicity of Amyloid-β
מאת: Kyle J. Korshavn, et al.
יצא לאור: (2017)

The Binding of Apolipoprotein E to Oligomers and Fibrils of Amyloid-β Alters the Kinetics of Amyloid Aggregation
מאת: Garai, Kanchan, et al.
יצא לאור: (2014)

The Binding of Apolipoprotein E to Oligomers and Fibrils of Amyloid-β Alters the Kinetics of Amyloid Aggregation
מאת: Kanchan Garai, et al.
יצא לאור: (2014)

Conversion of Aβ43 to Aβ40 by the successive action of angiotensin‐converting enzyme 2 and angiotensin‐converting enzyme
מאת: Shuyu Liu, et al.
יצא לאור: (2014)

Brazilin inhibits amyloid β-protein fibrillogenesis, remodels amyloid fibrils and reduces amyloid cytotoxicity
מאת: Du, Wen-Jie, et al.
יצא לאור: (2015)

Brazilin inhibits amyloid β-protein fibrillogenesis, remodels amyloid fibrils and reduces amyloid cytotoxicity
מאת: Wenjie Du, et al.
יצא לאור: (2015)

Cytotoxicity of Amyloid β1–42 Fibrils to Brain Immune Cells
מאת: Mikhail Matveyenka, et al.
יצא לאור: (2025)

Tanshinones Inhibit Amyloid Aggregation by Amyloid-β Peptide, Disaggregate Amyloid Fibrils, and Protect Cultured Cells
מאת: Wang, Qiuming, et al.
יצא לאור: (2013)

Tanshinones Inhibit Amyloid Aggregation by Amyloid-β Peptide, Disaggregate Amyloid Fibrils, and Protect Cultured Cells
מאת: Qiuming Wang, et al.
יצא לאור: (2013)

Amyloid β-Protein Is Degraded by Cellular Angiotensin-converting Enzyme (ACE) and Elevated by an ACE Inhibitor
מאת: Hemming, Matthew L., et al.
יצא לאור: (2005)

Kinetic and structural characterization of amyloid‐β peptide hydrolysis by human angiotensin‐1‐converting enzyme
מאת: Larmuth, Kate M., et al.
יצא לאור: (2016)

Amyloid β-Protein Is Degraded by Cellular Angiotensin-converting Enzyme (ACE) and Elevated by an ACE Inhibitor
מאת: Matthew L. Hemming, et al.
יצא לאור: (2005)

A New Motif in the N‐Terminal of Acetylcholinesterase Triggers Amyloid‐β Aggregation and Deposition
מאת: Hou, Li‐Na, et al.
יצא לאור: (2013)

Amyloid-β(1–42) Aggregation Initiates Its Cellular Uptake and Cytotoxicity
מאת: Jin, Sha, et al.
יצא לאור: (2016)

Amyloid-β(1–42) Aggregation Initiates Its Cellular Uptake and Cytotoxicity
מאת: Sha Jin, et al.
יצא לאור: (2016)

β‐Amyloid aggregation and heterogeneous nucleation
מאת: Srivastava, Atul K., et al.
יצא לאור: (2019)

β‐Amyloid aggregation and heterogeneous nucleation
מאת: Atul Srivastava, et al.
יצא לאור: (2019)

Aggregation and structure of amyloid β-protein
מאת: Kenjiro Ono, et al.
יצא לאור: (2021)

Inhibition of Amyloid β Protein Aggregation and Neurotoxicity by Rifampicin
מאת: Takami Tomiyama, et al.
יצא לאור: (1996)

Heparin Nanoparticles for β Amyloid Binding and Mitigation of β Amyloid Associated Cytotoxicity
מאת: Wang, Peng, et al.
יצא לאור: (2014)

Angiotensin-converting enzyme 2 is reduced in Alzheimer’s disease in association with increasing amyloid-β and tau pathology
מאת: Kehoe, Patrick Gavin, et al.
יצא לאור: (2016)