Angiotensin-converting Enzyme Degrades Alzheimer Amyloid β-Peptide (Aβ); Retards Aβ Aggregation, Deposition, Fibril Formation; and Inhibits Cytotoxicity

Angiotensin-converting Enzyme Degrades Alzheimer Amyloid β-Peptide (Aβ); Retards Aβ Aggregation, Deposition, Fibril Formation; and Inhibits Cytotoxicity

We have demonstrated that the angiotensin-converting enzyme (ACE) genotype is associated with Alzheimer's disease (AD) in the Japanese population (1Hu J. Miyatake F. Aizu Y. Nakagawa H. Nakamura S. Tamaoka A. Takahashi R. Urakami K. Shoji M. Neurosci. Lett. 1999; 277: 65-67Crossref PubMed Scopu...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Jianguo Hu, Akira Igarashi, Makiko Kamata, Hachiro Nakagawa
Μορφή:	Artigo
Γλώσσα:	Αγγλικά
Έκδοση:	2001
Διαθέσιμο Online:	https://doi.org/10.1074/jbc.m104068200 http://www.jbc.org/article/S0021925819402937/pdf
Ετικέτες:	Προσθήκη ετικέτας Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια

The N‐terminal active centre of human angiotensin‐converting enzyme degrades Alzheimer amyloid β‐peptide
από: Ryutaro Oba, κ.ά.
Έκδοση: (2005)

Angiotensin-Converting Enzyme Converts Amyloid β-Protein 1–42 (Aβ(1–42)) to Aβ(1–40), and Its Inhibition Enhances Brain Aβ Deposition
από: Zou, Kun, κ.ά.
Έκδοση: (2007)

Charge Dependent Retardation of Amyloid β Aggregation by Hydrophilic Proteins
από: Assarsson, Anna, κ.ά.
Έκδοση: (2014)

Charge Dependent Retardation of Amyloid β Aggregation by Hydrophilic Proteins
από: Anna Assarsson, κ.ά.
Έκδοση: (2014)

New Insights on How Metals Disrupt Amyloid β-Aggregation and Their Effects on Amyloid-β Cytotoxicity
από: Yuji Yoshiike, κ.ά.
Έκδοση: (2001)

Angiotensin-Converting Enzyme Converts Amyloid β-Protein 1–42 (Aβ<sub>1–42</sub>) to Aβ<sub>1–40</sub>, and Its Inhibition Enhances Brain Aβ Deposition
από: Kun Zou, κ.ά.
Έκδοση: (2007)

Preventing β-amyloid fibrillization and deposition: β-sheet breakers and pathological chaperone inhibitors
από: Wisniewski, Thomas, κ.ά.
Έκδοση: (2008)

Zinc as chaperone-mimicking agent for retardation of amyloid β peptide fibril formation
από: Abelein, Axel, κ.ά.
Έκδοση: (2015)

Zinc as chaperone-mimicking agent for retardation of amyloid β peptide fibril formation
από: Axel Abelein, κ.ά.
Έκδοση: (2015)

Microglia convert aggregated amyloid-β into neurotoxic forms through the shedding of microvesicles
από: Joshi, P, κ.ά.
Έκδοση: (2014)

Microglia convert aggregated amyloid-β into neurotoxic forms through the shedding of microvesicles
από: P. Joshi, κ.ά.
Έκδοση: (2013)

Aβ42-to-Aβ40- and Angiotensin-converting Activities in Different Domains of Angiotensin-converting Enzyme
από: Zou, Kun, κ.ά.
Έκδοση: (2009)

Aβ42-to-Aβ40- and Angiotensin-converting Activities in Different Domains of Angiotensin-converting Enzyme
από: Kun Zou, κ.ά.
Έκδοση: (2009)

TMPyP Inhibits Amyloid-β Aggregation and Alleviates Amyloid-Induced Cytotoxicity
από: Fan, Yujuan, κ.ά.
Έκδοση: (2017)

Regulation of Steady-state β-Amyloid Levels in the Brain by Neprilysin and Endothelin-converting Enzyme but Not Angiotensin-converting Enzyme
από: Elizabeth A. Eckman, κ.ά.
Έκδοση: (2006)

The Serpin-Enzyme Complex Receptor Recognizes Soluble, Nontoxic Amyloid-β Peptide but Not Aggregated, Cytotoxic Amyloid-β Peptide
από: Kimberly Boland, κ.ά.
Έκδοση: (1996)

TDP-43 expression influences amyloid β plaque deposition and tau aggregation
από: Davis, Stephani A., κ.ά.
Έκδοση: (2017)

TDP-43 expression influences amyloidβ plaque deposition and tau aggregation
από: Stephani A. Davis, κ.ά.
Έκδοση: (2017)

Reduced Lipid Bilayer Thickness Regulates the Aggregation and Cytotoxicity of Amyloid-β
από: Korshavn, Kyle J., κ.ά.
Έκδοση: (2017)

Reduced Lipid Bilayer Thickness Regulates the Aggregation and Cytotoxicity of Amyloid-β
από: Kyle J. Korshavn, κ.ά.
Έκδοση: (2017)

The Binding of Apolipoprotein E to Oligomers and Fibrils of Amyloid-β Alters the Kinetics of Amyloid Aggregation
από: Garai, Kanchan, κ.ά.
Έκδοση: (2014)

The Binding of Apolipoprotein E to Oligomers and Fibrils of Amyloid-β Alters the Kinetics of Amyloid Aggregation
από: Kanchan Garai, κ.ά.
Έκδοση: (2014)

Conversion of Aβ43 to Aβ40 by the successive action of angiotensin‐converting enzyme 2 and angiotensin‐converting enzyme
από: Shuyu Liu, κ.ά.
Έκδοση: (2014)

Brazilin inhibits amyloid β-protein fibrillogenesis, remodels amyloid fibrils and reduces amyloid cytotoxicity
από: Du, Wen-Jie, κ.ά.
Έκδοση: (2015)

Brazilin inhibits amyloid β-protein fibrillogenesis, remodels amyloid fibrils and reduces amyloid cytotoxicity
από: Wenjie Du, κ.ά.
Έκδοση: (2015)

Cytotoxicity of Amyloid β1–42 Fibrils to Brain Immune Cells
από: Mikhail Matveyenka, κ.ά.
Έκδοση: (2025)

Tanshinones Inhibit Amyloid Aggregation by Amyloid-β Peptide, Disaggregate Amyloid Fibrils, and Protect Cultured Cells
από: Wang, Qiuming, κ.ά.
Έκδοση: (2013)

Tanshinones Inhibit Amyloid Aggregation by Amyloid-β Peptide, Disaggregate Amyloid Fibrils, and Protect Cultured Cells
από: Qiuming Wang, κ.ά.
Έκδοση: (2013)

Amyloid β-Protein Is Degraded by Cellular Angiotensin-converting Enzyme (ACE) and Elevated by an ACE Inhibitor
από: Hemming, Matthew L., κ.ά.
Έκδοση: (2005)

Kinetic and structural characterization of amyloid‐β peptide hydrolysis by human angiotensin‐1‐converting enzyme
από: Larmuth, Kate M., κ.ά.
Έκδοση: (2016)

Amyloid β-Protein Is Degraded by Cellular Angiotensin-converting Enzyme (ACE) and Elevated by an ACE Inhibitor
από: Matthew L. Hemming, κ.ά.
Έκδοση: (2005)

A New Motif in the N‐Terminal of Acetylcholinesterase Triggers Amyloid‐β Aggregation and Deposition
από: Hou, Li‐Na, κ.ά.
Έκδοση: (2013)

Amyloid-β(1–42) Aggregation Initiates Its Cellular Uptake and Cytotoxicity
από: Jin, Sha, κ.ά.
Έκδοση: (2016)

Amyloid-β(1–42) Aggregation Initiates Its Cellular Uptake and Cytotoxicity
από: Sha Jin, κ.ά.
Έκδοση: (2016)

β‐Amyloid aggregation and heterogeneous nucleation
από: Srivastava, Atul K., κ.ά.
Έκδοση: (2019)

β‐Amyloid aggregation and heterogeneous nucleation
από: Atul Srivastava, κ.ά.
Έκδοση: (2019)

Aggregation and structure of amyloid β-protein
από: Kenjiro Ono, κ.ά.
Έκδοση: (2021)

Inhibition of Amyloid β Protein Aggregation and Neurotoxicity by Rifampicin
από: Takami Tomiyama, κ.ά.
Έκδοση: (1996)

Heparin Nanoparticles for β Amyloid Binding and Mitigation of β Amyloid Associated Cytotoxicity
από: Wang, Peng, κ.ά.
Έκδοση: (2014)

Angiotensin-converting enzyme 2 is reduced in Alzheimer’s disease in association with increasing amyloid-β and tau pathology
από: Kehoe, Patrick Gavin, κ.ά.
Έκδοση: (2016)