Myogenic-specific ablation of Fgfr1 impairs FGF2-mediated proliferation of satellite cells at the myofiber niche but does not abolish the capacity for muscle regeneration
Skeletal muscle satellite cells (SCs) are Pax7(+) myogenic stem cells that reside between the basal lamina and the plasmalemma of the myofiber. In mature muscles, SCs are typically quiescent, but can be activated in response to muscle injury. Depending on the magnitude of tissue trauma, SCs may divi...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | engelsk |
| Udgivet: |
2015
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| Online adgang: | https://doi.org/10.3389/fnagi.2015.00085 https://www.frontiersin.org/articles/10.3389/fnagi.2015.00085/pdf |
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