Myogenic-specific ablation of Fgfr1 impairs FGF2-mediated proliferation of satellite cells at the myofiber niche but does not abolish the capacity for muscle regeneration

Skeletal muscle satellite cells (SCs) are Pax7(+) myogenic stem cells that reside between the basal lamina and the plasmalemma of the myofiber. In mature muscles, SCs are typically quiescent, but can be activated in response to muscle injury. Depending on the magnitude of tissue trauma, SCs may divi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zipora Yablonka‐Reuveni, Maria Elena Danoviz, Michael Phelps, Pascal Stuelsatz
Fformat: Artigo
Iaith:Saesneg
Cyhoeddwyd: 2015
Mynediad Ar-lein:https://doi.org/10.3389/fnagi.2015.00085
https://www.frontiersin.org/articles/10.3389/fnagi.2015.00085/pdf
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