Induction of Distinct TLR2-Mediated Proinflammatory and Proadhesive Signaling Pathways in Response to <i>Porphyromonas gingivalis</i> Fimbriae

Induction of Distinct TLR2-Mediated Proinflammatory and Proadhesive Signaling Pathways in Response to <i>Porphyromonas gingivalis</i> Fimbriae

The oral pathogen Porphyromonas gingivalis, as well as its purified fimbriae, are known to activate TLR2 and induce proinflammatory and proadhesive effects. The TLR2 proinflammatory pathway induces NF-kappaB-dependent inflammatory cytokines, whereas the TLR2 proadhesive pathway is characterized by i...

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Библиографические подробности
Главные авторы:	George Hajishengallis, Min Wang, Shuang Liang
Формат:	Artigo
Язык:	английский
Опубликовано:	2009
Online-ссылка:	https://doi.org/10.4049/jimmunol.0900524 https://journals.aai.org/jimmunol/article-pdf/182/11/6690/1268381/zim01109006690.pdf
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