The domain architecture of large guanine nucleotide exchange factors for the small GTP-binding protein Arf

Small G proteins, which are essential regulators of multiple cellular functions, are activated by guanine nucleotide exchange factors (GEFs) that stimulate the exchange of the tightly bound GDP nucleotide by GTP. The catalytic domain responsible for nucleotide exchange is in general associated with...

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Auteurs principaux: Barbara Mouratou, Valérie Biou, Alexandra Joubert, Jean Cohen, David J. Shields, Niko Geldner, Gerd Jürgens, Paul Melançon, Jacqueline Cherfils
Format: Artigo
Langue:anglais
Publié: 2005
Accès en ligne:https://doi.org/10.1186/1471-2164-6-20
https://bmcgenomics.biomedcentral.com/counter/pdf/10.1186/1471-2164-6-20
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