Phosphoinositide 3-Kinase γ Is a Mediator of Gβγ-dependent Jun Kinase Activation
Jun kinases (JNK) are involved in the stress response of mammalian cells. Stimulation of JNK can be induced by stress factors and by agonists of tyrosine kinase and G protein-coupled receptors. G protein-dependent receptors stimulate JNK via Gβγ subunits of heterotrimeric G proteins, but the subsequ...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
1998
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| Online Access: | https://doi.org/10.1074/jbc.273.5.2505 http://www.jbc.org/article/S0021925818949240/pdf |
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