Phosphoinositide 3-Kinase γ Is a Mediator of Gβγ-dependent Jun Kinase Activation

Jun kinases (JNK) are involved in the stress response of mammalian cells. Stimulation of JNK can be induced by stress factors and by agonists of tyrosine kinase and G protein-coupled receptors. G protein-dependent receptors stimulate JNK via Gβγ subunits of heterotrimeric G proteins, but the subsequ...

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Bibliografische gegevens
Hoofdauteurs: Marco López-Ilasaca, J. Silvio Gutkind, Reinhard Wetzker
Formaat: Artigo
Taal:Engels
Gepubliceerd in: 1998
Online toegang:https://doi.org/10.1074/jbc.273.5.2505
http://www.jbc.org/article/S0021925818949240/pdf
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