Phosphoinositide 3-Kinase γ Is a Mediator of Gβγ-dependent Jun Kinase Activation

Jun kinases (JNK) are involved in the stress response of mammalian cells. Stimulation of JNK can be induced by stress factors and by agonists of tyrosine kinase and G protein-coupled receptors. G protein-dependent receptors stimulate JNK via Gβγ subunits of heterotrimeric G proteins, but the subsequ...

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Autors principals: Marco López-Ilasaca, J. Silvio Gutkind, Reinhard Wetzker
Format: Artigo
Idioma:anglès
Publicat: 1998
Accés en línia:https://doi.org/10.1074/jbc.273.5.2505
http://www.jbc.org/article/S0021925818949240/pdf
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