Phase 2 trial of sorafenib in children and young adults with refractory solid tumors: A report from the Children's Oncology Group

Background Sorafenib is an oral small molecule inhibitor of multiple kinases controlling tumor growth and angiogenesis. The purpose of the phase 2 study was to determine the response rate of sorafenib and gain further information on the associated toxicities, pharmacokinetics, and pharmacodynamics o...

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Bibliographic Details
Main Authors: AeRang Kim, Brigitte C. Widemann, Mark Krailo, Nalini Jayaprakash, Elizabeth Fox, Brenda J. Weigel, Susan M. Blaney
Format: Artigo
Language:English
Published: 2015
Online Access:https://doi.org/10.1002/pbc.25548
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