Activation of MAP kinases by calcium-dependent and calcium-independent pathways. Stimulation by thapsigargin and epidermal growth factor.
In order to determine the effect of calcium mobilization on mitogen-activated protein (MAP) kinase activation, we have treated human foreskin fibroblasts (HSWP cells) and human epidermal carcinoma (A431) cells with thapsigargin. Intracellular free calcium was monitored by single cell image analysis...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
1992
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| Online Access: | https://doi.org/10.1016/s0021-9258(19)88637-4 |
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