MYC‐associated and double‐hit lymphomas: A review of pathobiology, prognosis, and therapeutic approaches

Aberrant expression of the v‐myc avian myelocytomatosis viral oncogene homolog (MYC) proto‐oncogene has known transformative potential in healthy human cells. Chromosomal MYC rearrangements and consequent MYC overexpression is the defining lesion in Burkitt lymphoma (BL), conferring a highly prolife...

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Main Authors: Adam M. Petrich, Chadi Nabhan, Sonali M. Smith
格式: Revisão
語言:英语
出版: 2014
在線閱讀:https://doi.org/10.1002/cncr.28899
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