Relations between factor VIIa binding and expression of factor VIIa/tissue factor catalytic activity on cell surfaces.
The kinetics of the binding of rVIIa to cell surface tissue factor (TF) and the resultant expression of VIIa/TF activity were studied. Binding of 125I-rVIIa (10 nM) to cell surface TF required 30-60 min for saturation, whereas VIIa/TF activity was fully expressed toward factor X (F X) on intact mono...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | anglès |
| Publicat: |
1992
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| Accés en línia: | https://doi.org/10.1016/s0021-9258(19)49554-9 |
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