Cutting Edge: Physiologic Attenuation of Proinflammatory Transcription by the Gs Protein-Coupled A2A Adenosine Receptor In Vivo

The A2A adenosine receptor plays a critical role in the physiologic immunosuppressive pathway that protects normal tissues from excessive collateral damage by overactive immune cells and their proinflammatory cytokines. In this study, we examine and clarify the mechanism of tissue protection by extr...

Full description

Saved in:
Bibliographic Details
Main Authors: Dmitriy Lukashev, Akio Ohta, Sergey Apasov, Jiang‐Fan Chen, Michail V. Sitkovsky
Format: Artigo
Language:English
Published: 2004
Online Access:https://doi.org/10.4049/jimmunol.173.1.21
https://journals.aai.org/jimmunol/article-pdf/173/1/21/1186905/21.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!