Identification of 5‘ and 3‘ sequences involved in the regulation of transcription of the human mdr1 gene in vivo.
The human mdrl gene encodes a putative drug efflux pump (P-glycoprotein) whose overexpression is associated with the development of multidrug resistance (MDR).The promoter and 5"flanking DNA of this gene were isolated from a human genomic DNA library and used to prepare a series of chlorampheni...
Uloženo v:
Hlavní autoři: | , , , , , |
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Médium: | Artigo |
Jazyk: | angličtina |
Vydáno: |
1993
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On-line přístup: | https://doi.org/10.1016/s0021-9258(18)53095-7 |
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