Identification of 5‘ and 3‘ sequences involved in the regulation of transcription of the human mdr1 gene in vivo.

The human mdrl gene encodes a putative drug efflux pump (P-glycoprotein) whose overexpression is associated with the development of multidrug resistance (MDR).The promoter and 5"flanking DNA of this gene were isolated from a human genomic DNA library and used to prepare a series of chlorampheni...

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Hlavní autoři: Mary Madden, Charles S. Morrow, Masayuki Nakagawa, Merrill E. Goldsmith, C.R. Fairchild, Kenneth H. Cowan
Médium: Artigo
Jazyk:angličtina
Vydáno: 1993
On-line přístup:https://doi.org/10.1016/s0021-9258(18)53095-7
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