ER stress induces NLRP3 inflammasome activation and hepatocyte death

ER stress induces NLRP3 inflammasome activation and hepatocyte death

Abstract The incidence of chronic liver disease is constantly increasing, owing to the obesity epidemic. However, the causes and mechanisms of inflammation-mediated liver damage remain poorly understood. Endoplasmic reticulum (ER) stress is an initiator of cell death and inflammatory mechanisms. Alt...

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Main Authors: Cynthia Lebeaupin, Emma Proïcs, C H D de Bieville, Denis Rousseau, Stéphanie Bonnafous, Stéphanie Patouraux, Gilbert Adam, Vanessa Lavallard, Carole Rovère, Ophélia Le Thuc, Marie‐Christine Saint‐Paul, Rodolphe Anty, Anne-Sophie Schneck, Antonio Iannelli, Jean Gugenheim, Albert Tran, Philippe Gual, Béatrice Bailly-Maître
Format: Artigo
Language:English
Published: 2015
Online Access:https://doi.org/10.1038/cddis.2015.248
https://www.nature.com/articles/cddis2015248.pdf
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https://doi.org/10.1038/cddis.2015.248
https://www.nature.com/articles/cddis2015248.pdf

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