Hepatitis B Virus X Protein Inhibits Tumor Suppressor miR-205 through Inducing Hypermethylation of miR-205 Promoter to Enhance Carcinogenesis

The infection of hepatitis B virus (HBV) is closely associated with the development of hepatocellular carcinoma (HCC), in which HBV X protein (HBx) plays crucial roles. MicroRNAs are involved in diverse biologic functions and in carcinogenesis by regulating gene expression. In the present study, we...

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Hlavní autoři: Tao Zhang, Junping Zhang, Ming Cui, Fabao Liu, Xiaona You, Yumei Du, Yuen Gao, Shuai Zhang, Zhanping Lu, Lihong Ye, Xiaodong Zhang
Médium: Artigo
Jazyk:angličtina
Vydáno: 2013
On-line přístup:https://doi.org/10.1593/neo.131362
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