Guanylate cyclase from bovine lung. A kinetic analysis of the regulation of the purified soluble enzyme by protoporphyrin IX, heme, and nitrosyl-heme.

A kinetic characterization of the regulation of purified soluble guanylate cyclase from bovine lung by protoporphyrin M and hematin is reported.Purified guanylate cyclase was isolated with heme and had specific activities @mol of cGMP/min/mg of protein) of 0.1-0.2 and 0.3-0.6 in the presence of exce...

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Main Authors: Michael S. Wolin, K S Wood, L J Ignarro
Format: Artigo
Jezik:angleščina
Izdano: 1982
Online dostop:https://doi.org/10.1016/s0021-9258(18)33448-3
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